ELI5: Depuis, les bénéfices du cisplatine en termes de survie ne sont plus à démontrer et cette molécule possède une autorisation de mise sur le marché (AMM) pour le traitement des cancers testiculaires, ovariens, de la sphère ORL, de l’œsophage, du col utérin, de l’endomètre, de la vessie.

This sentence means that a medicine called cisplatin works so well at saving lives that doctors already have all the proof they need, and safety experts have officially given it a green light to treat several different types of cancer.

Imagine your body is a busy neighborhood, and cancer cells are bad weeds spreading across different gardens and choking out the flowers. Cisplatin is like a super-effective weed killer that the neighborhood council has officially tested and approved for safety. Because it has saved so many gardens in the past, nobody questions whether it works anymore—it is already a trusted tool in the shed.

The official approval mentioned in the text (called an AMM in French, which is just like an official safety permit from the government) says this specific medicine is allowed to clean up "weeds" in several specific parts of the body:

• Boy parts and girl parts: It treats cancers in the testicles, ovaries, and the lower and inner parts of the womb (cervix and endometrium).
• The eating and breathing tubes: It helps with cancers in the throat, mouth, nose, and the food pipe (esophagus) that connects your mouth to your stomach.
• The water tank: It also treats cancer in the bladder, which is the organ that holds your pee.